Rituximab efficiently depletes B cells in lung tumors and normal lung tissue [version 1; referees: 2 approved]
Rituximab is a monoclonal antibody that targets the CD20 B-cell-specific antigen and is widely used as therapy for B-cell lymphoma. Since rituximab depletes both malignant and normal B cells, it is increasingly being used to treat various conditions in which normal B cells have a pathogenic role, su...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2016-01-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/5-38/v1 |