Treating seizures and epilepsy with anticoagulants?

Thrombin is a serine protease playing an essential role in the blood coagulation cascade. Recent work, however, has identified a novel role for thrombin-mediated signaling pathways in the central nervous system. Binding of thrombin to protease-activated receptors (PARs) in the brain appears to have...

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Bibliographic Details
Main Authors: Nicola eMaggio, Ilan eBlatt, Andreas eVlachos, David eTanne, Joab eChapman, Menahem eSegal
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00019/full