Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression
Abstract Sepsis is a life-threatening cascading systemic inflammatory response syndrome on account of serve infection. In inflamed tissues, activated macrophages generate large amounts of inflammatory cytokines reactive species, and are exposed to the damaging effects of reactive species. However, c...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00571-4 |