Experimental models and tools to tackle glioblastoma

Experimental models and tools to tackle glioblastoma

Glioblastoma multiforme (GBM) is one of the deadliest human cancers. Despite increasing knowledge of the genetic and epigenetic changes that underlie tumour initiation and growth, the prognosis for GBM patients remains dismal. Genome analysis has failed to lead to success in the clinic. Fresh approa...

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Bibliographic Details
Main Authors: Faye L. Robertson, Maria-Angeles Marqués-Torrejón, Gillian M. Morrison, Steven M. Pollard
Format: Article
Language:English
Published: The Company of Biologists 2019-09-01
Series:Disease Models & Mechanisms
Subjects:
Central nervous system
In vitro
CRISPR/Cas9
Mouse
Human
Xenograft
GBM
Cancer
Brain tumour
Online Access:http://dmm.biologists.org/content/12/9/dmm040386

Internet

http://dmm.biologists.org/content/12/9/dmm040386

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