Down-regulation of GRP78 Enhances Chemotherapy Sensitivity to VP-16 in Lung Adenocarcinoma

Background and objective GRP78, a member of GRPs, plays a critical role in chemotherapy resistance in some cancers. To investigate the relationship between the expression of GRP78 and resistance to anti-cancer drug VP-16 in vitro in lung adenocarcinoma SPCA-1 cell line. Methods SPCA-1 cells were div...

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Bibliographic Details
Main Authors: Li JIANG, Lichuan ZHANG, Qi WANG, Siyan WANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2009-11-01
Series:Chinese Journal of Lung Cancer
Subjects:
Online Access:http://www.lungca.org/index.php?journal=01&page=article&op=viewFile&path[]=10.3779%2Fj.issn.1009-3419.2009.11.06&path[]=1193