An Experimental Approach to Rigorously Assess Paneth Cell α-Defensin (Defa) mRNA Expression in C57BL/6 Mice

Abstract Abundant evidence from many laboratories supports the premise that α-defensin peptides secreted from Paneth cells are key mediators of host-microbe interactions in the small intestine that contribute to host defense and homeostasis. α-defensins are among the most highly expressed antimicrob...

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Bibliographic Details
Main Authors: Patricia A. Castillo, Eric B. Nonnecke, Daniel T. Ossorio, Michelle T. N. Tran, Stephanie M. Goley, Bo Lönnerdal, Mark A. Underwood, Charles L. Bevins
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-49471-9