Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblast migration in the mouse brain after stroke

Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblast migration in the mouse brain after stroke

Abstract Background Osteopontin (OPN), an acidic phosphoglycoprotein, is upregulated in the brain after cerebral ischemia. We previously reported that OPN supports migration, survival, and proliferation of neural stem cells (NSC) in primary cell culture, as well as their differentiation into neurons...

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Bibliographic Details
Main Authors: Rebecca Rogall, Monika Rabenstein, Sabine Vay, Annika Bach, Anton Pikhovych, Johannes Baermann, Mathias Hoehn, Sébastien Couillard-Despres, Gereon Rudolf Fink, Michael Schroeter, Maria Adele Rueger
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Stem Cell Research & Therapy
Subjects:
Doublecortin
Microglia
Neural progenitor cells
Photothrombosis
Online Access:http://link.springer.com/article/10.1186/s13287-018-0927-9

Internet

http://link.springer.com/article/10.1186/s13287-018-0927-9

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