Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin

Abstract Background Photodynamic therapy with a photosensitizer such as protoporphyrin-IX, a light sensitive metabolite of heme synthesis, is a highly selective treatment for various carcinomas. In previous studies, we found a significant down regulation of the relevant enzyme ferrochelatase in gast...

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Bibliographic Details
Main Authors: Bernhard Gillissen, Antje Richter, Frank Essmann, Wolfgang Kemmner
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-08667-x