Developing a Comparative Docking Protocol for the Prediction of Peptide Selectivity Profiles: Investigation of Potassium Channel Toxins

During the development of selective peptides against highly homologous targets, a reliable tool is sought that can predict information on both mechanisms of binding and relative affinities. These tools must first be tested on known profiles before application on novel therapeutic candidates. We ther...

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Bibliographic Details
Main Authors: Serdar Kuyucak, Po-Chia Chen
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/4/2/110/