Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits.

Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits.

Neutrophil-derived networks of DNA-composed extracellular fibers covered with antimicrobial molecules, referred to as neutrophil extracellular traps (NETs), are recognized as a physiological microbicidal mechanism of innate immunity. The formation of NETs is also classified as a model of a cell deat...

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Bibliographic Details
Main Authors: Danuta Bryzek, Izabela Ciaston, Ewelina Dobosz, Anna Gasiorek, Anna Makarska, Michal Sarna, Sigrun Eick, Magdalena Puklo, Maciej Lech, Barbara Potempa, Jan Potempa, Joanna Koziel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007773

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https://doi.org/10.1371/journal.ppat.1007773

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