Plasmatic carbonic anhydrase IX as a diagnostic marker for clear cell renal cell carcinoma

Plasmatic carbonic anhydrase IX as a diagnostic marker for clear cell renal cell carcinoma

Carbonic anhydrase (CA, EC 4.2.1.1) IX is regarded as a tumour hypoxia marker and CA inhibitors have been proposed as a new class of antitumor agents, with one such agent in Phase II clinical trials. The expression of some CAs, in particular the isoforms CA IX and CA XII, has been correlated with tu...

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Bibliographic Details
Main Authors: Laura Lucarini, Lucia Magnelli, Nicola Schiavone, Alfonso Crisci, Alessio Innocenti, Luca Puccetti, Fabio Cianchi, Sara Peri, Claudiu T. Supuran, Laura Papucci, Emanuela Masini
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Carbonic anhydrase
isoform IX
tumours
clear cell renal cell carcinoma
Online Access:http://dx.doi.org/10.1080/14756366.2017.1411350

Internet

http://dx.doi.org/10.1080/14756366.2017.1411350

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