GMP-Compliant Isolation and Expansion of Bone Marrow-Derived MSCs in the Closed, Automated Device Quantum Cell Expansion System
The estimated frequency of MSCs in BM is about 0.001–0.01% of total nucleated cells. Most commonly, one applied therapeutic cell dose is about 1–5 million MSCs/kg body weight, necessitating a reliable, fast, and safe expansion system. The limited availability of MSCs demands for an extensive ex vivo...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-11-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368912X657990 |