Sevoflurane Inhibits Traumatic Brain Injury-Induced Neuron Apoptosis via EZH2-Downregulated KLF4/p38 Axis

Sevoflurane Inhibits Traumatic Brain Injury-Induced Neuron Apoptosis via EZH2-Downregulated KLF4/p38 Axis

Traumatic brain injury (TBI) is characterized by physical damage to the brain tissues, ensuing transitory or permanent neurological dysfunction featured with neuronal loss and subsequent brain damage. Sevoflurane, a widely used halogenated anesthetic in clinical settings, has been reported to allevi...

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Bibliographic Details
Main Authors: Zhongyu Wang, Juan Li, Anqi Wang, Zhaoyang Wang, Junmin Wang, Jingjing Yuan, Xin Wei, Fei Xing, Wei Zhang, Na Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
sevoflurane
traumatic brain injury
enhancer of zeste homolog 2
Krüppel-like factor 4
p38-mitogen-activated protein kinase pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.658720/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.658720/full

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