Fixel-Based Analysis Effectively Identifies White Matter Tract Degeneration in Huntington’s Disease

Fixel-Based Analysis Effectively Identifies White Matter Tract Degeneration in Huntington’s Disease

Microstructure damage in white matter might be linked to regional and global atrophy in Huntington’s Disease (HD). We hypothesize that degeneration of subcortical regions, including the basal ganglia, is associated with damage of white matter tracts linking these affected regions. We aim to use fixe...

Full description

Bibliographic Details
Main Authors: Sher Li Oh, Chiung-Mei Chen, Yih-Ru Wu, Maria Valdes Hernandez, Chih-Chien Tsai, Jur-Shan Cheng, Yao-Liang Chen, Yi-Ming Wu, Yu-Chun Lin, Jiun-Jie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Neuroscience
Subjects:
fixel-based analysis
Huntington’s Disease
diffusion-tensor imaging
magnetic resonance imaging
neurodegeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.711651/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.711651/full

Similar Items