Modeling Human Antitumor Responses In Vivo Using Umbilical Cord Blood-Engrafted Mice

Mice engrafted with human immune cells offer powerful in vivo model systems to investigate molecular and cellular processes of tumorigenesis, as well as to test therapeutic approaches to treat the resulting cancer. The use of umbilical cord blood mononuclear cells as a source of human immune cells f...

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Bibliographic Details
Main Authors: Nicholas A. Zumwalde, Jenny E. Gumperz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00054/full