The regulated secretory pathway and human disease: insights from gene variants and single nucleotide polymorphisms

The regulated secretory pathway provides critical control of peptide, growth factor, and hormone release from neuroendocrine and endocrine cells, and neurons, maintaining physiological homeostasis. Propeptides and prohormones are packaged into dense core granules (DCGs), where they frequently under...

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Bibliographic Details
Main Authors: Stephen eSalton, Wei Jye Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00096/full