Amplification and Over-Expression of the MDM2 Gene in Human Soft Tissue Tumours
Purpose. Amplification of genetic sequences on chromosome 12q13 is frequently found in soft tissue tumours. However, for the MDM2 gene, over-expression of the MDM2 protein has not always been shown to accompany gene amplification, raising the possibility that amplification of genetic sequences targe...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1997-01-01
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Series: | Sarcoma |
Online Access: | http://dx.doi.org/10.1080/13577149778434 |