Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid

3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are...

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Main Authors: Abu Zafar Al Munsur, Harendra Nath Roy, Mohinuddin Khan Imon
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535220304056
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spelling doaj-2e957a4cae1e4c6f80f1c849fa3727182020-12-03T04:30:50ZengElsevierArabian Journal of Chemistry1878-53522020-12-01131288078814Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acidAbu Zafar Al Munsur0Harendra Nath Roy1Mohinuddin Khan Imon2Department of Chemistry, University of Rajshahi, Rajshahi 6205, Bangladesh; Organic Material Synthesis Division, Kayrbat Research Institute (KRI), Bogra 5810, Bangladesh; Corresponding author at: Organic Material Synthesis Division, Kayrbat Research Institute (KRI), Bogra 5810, Bangladesh.Department of Chemistry, University of Rajshahi, Rajshahi 6205, BangladeshDepartment of Chemistry, University of Rajshahi, Rajshahi 6205, Bangladesh3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are easy purification, cost-effectiveness, and high yielding, above all environmentally benign protocol.http://www.sciencedirect.com/science/article/pii/S1878535220304056Imidazole3-Picolinic acidMetal-freeOrgano-catalystGreen synthesis
collection DOAJ
language English
format Article
sources DOAJ
author Abu Zafar Al Munsur
Harendra Nath Roy
Mohinuddin Khan Imon
spellingShingle Abu Zafar Al Munsur
Harendra Nath Roy
Mohinuddin Khan Imon
Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
Arabian Journal of Chemistry
Imidazole
3-Picolinic acid
Metal-free
Organo-catalyst
Green synthesis
author_facet Abu Zafar Al Munsur
Harendra Nath Roy
Mohinuddin Khan Imon
author_sort Abu Zafar Al Munsur
title Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
title_short Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
title_full Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
title_fullStr Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
title_full_unstemmed Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
title_sort highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
publisher Elsevier
series Arabian Journal of Chemistry
issn 1878-5352
publishDate 2020-12-01
description 3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are easy purification, cost-effectiveness, and high yielding, above all environmentally benign protocol.
topic Imidazole
3-Picolinic acid
Metal-free
Organo-catalyst
Green synthesis
url http://www.sciencedirect.com/science/article/pii/S1878535220304056
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AT harendranathroy highlyefficientandmetalfreesynthesisoftriandtetrasubstitutedimidazolecatalyzedby3picolinicacid
AT mohinuddinkhanimon highlyefficientandmetalfreesynthesisoftriandtetrasubstitutedimidazolecatalyzedby3picolinicacid
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