Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are...
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doaj-2e957a4cae1e4c6f80f1c849fa3727182020-12-03T04:30:50ZengElsevierArabian Journal of Chemistry1878-53522020-12-01131288078814Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acidAbu Zafar Al Munsur0Harendra Nath Roy1Mohinuddin Khan Imon2Department of Chemistry, University of Rajshahi, Rajshahi 6205, Bangladesh; Organic Material Synthesis Division, Kayrbat Research Institute (KRI), Bogra 5810, Bangladesh; Corresponding author at: Organic Material Synthesis Division, Kayrbat Research Institute (KRI), Bogra 5810, Bangladesh.Department of Chemistry, University of Rajshahi, Rajshahi 6205, BangladeshDepartment of Chemistry, University of Rajshahi, Rajshahi 6205, Bangladesh3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are easy purification, cost-effectiveness, and high yielding, above all environmentally benign protocol.http://www.sciencedirect.com/science/article/pii/S1878535220304056Imidazole3-Picolinic acidMetal-freeOrgano-catalystGreen synthesis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abu Zafar Al Munsur Harendra Nath Roy Mohinuddin Khan Imon |
spellingShingle |
Abu Zafar Al Munsur Harendra Nath Roy Mohinuddin Khan Imon Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid Arabian Journal of Chemistry Imidazole 3-Picolinic acid Metal-free Organo-catalyst Green synthesis |
author_facet |
Abu Zafar Al Munsur Harendra Nath Roy Mohinuddin Khan Imon |
author_sort |
Abu Zafar Al Munsur |
title |
Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid |
title_short |
Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid |
title_full |
Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid |
title_fullStr |
Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid |
title_full_unstemmed |
Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid |
title_sort |
highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid |
publisher |
Elsevier |
series |
Arabian Journal of Chemistry |
issn |
1878-5352 |
publishDate |
2020-12-01 |
description |
3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are easy purification, cost-effectiveness, and high yielding, above all environmentally benign protocol. |
topic |
Imidazole 3-Picolinic acid Metal-free Organo-catalyst Green synthesis |
url |
http://www.sciencedirect.com/science/article/pii/S1878535220304056 |
work_keys_str_mv |
AT abuzafaralmunsur highlyefficientandmetalfreesynthesisoftriandtetrasubstitutedimidazolecatalyzedby3picolinicacid AT harendranathroy highlyefficientandmetalfreesynthesisoftriandtetrasubstitutedimidazolecatalyzedby3picolinicacid AT mohinuddinkhanimon highlyefficientandmetalfreesynthesisoftriandtetrasubstitutedimidazolecatalyzedby3picolinicacid |
_version_ |
1724401476828135424 |