Highly efficient and metal-free synthesis of tri- and tetrasubstituted imidazole catalyzed by 3-picolinic acid
3-Picolinic acid is an efficient organo-catalyst for a one-pot three-component synthesis of 2,4,5-triaryl substituted imidazole. Moreover, the utility of this catalyst has been extended to the four-component synthesis of 1,2,4,5-tetra-substituted imidazole. The pivotal advantages of this process are...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | Arabian Journal of Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535220304056 |