Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure

Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure

The onset and mechanisms underlying neurodegenerative diseases remain uncertain. The main features of neurodegenerative diseases have been related with cellular and molecular events like neuronal loss, mitochondrial dysfunction and aberrant accumulation of misfolded proteins or peptides in specific...

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Bibliographic Details
Main Authors: Jessica D Panes, Aline Wendt, Oscar Ramirez-Molina, Patricio A Castro, Jorge Fuentealba
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease; amyotrophic lateral sclerosis; huntington’s disease; mitochondrial dysfunction; parkinson’s disease; pgc-1α; synaptic function; vascular dementia
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=2;spage=237;epage=245;aulast=Panes

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=2;spage=237;epage=245;aulast=Panes

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