Differential Effects of Superoxide Dismutase Mimetics after Mechanical Overload of Articular Cartilage

Post-traumatic osteoarthritis can develop as a result of the initial mechanical impact causing the injury and also as a result of chronic changes in mechanical loading of the joint. Aberrant mechanical loading initiates excessive production of reactive oxygen species, oxidative damage, and stress th...

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Bibliographic Details
Main Authors: Mitchell C. Coleman, Marc J. Brouillette, Nicholas S. Andresen, Rebecca E. Oberley-Deegan, James M. Martin
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/6/4/98