Safety evaluation of MCC1274 via oral toxicity tests in rats

In this study, the safety of Bifidobacterium breve MCC1274, a probiotic bifidobacterial strain, was assessed by single-dose and 90-day repeated-dose oral toxicity studies. In the single-dose oral toxicity assay using 6000 mg/kg of B. breve MCC1274 corresponding to 8.4 × 10 11 colony-forming unit (CF...

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Bibliographic Details
Main Authors: Satoshi Arai, Jun-ichi Minami, Masamichi Muto, Noriyuki Iwabuchi, Koji Yamauchi, Jin-zhong Xiao, Fumiaki Abe
Format: Article
Language:English
Published: SAGE Publishing 2018-11-01
Series:Toxicology Research and Application
Online Access:https://doi.org/10.1177/2397847318807373