Natural and Tumor Induced Regulatory T-cells in Malignant Glioma

Natural and Tumor Induced Regulatory T-cells in Malignant Glioma

One of the hallmark features of glioblastoma multiforme (GBM), the most common adult primary brain tumor with a very dismal prognosis, is the accumulation of CD4+CD25+Foxp3+ regulatory T cells (Tregs). Regulatory T cells (Tregs) segregate into two primary categories: thymus-derived natural Tregs (nT...

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Bibliographic Details
Main Author: Maciej eLesniak
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Immunology
Subjects:
regulatory T-cells
Tregs
malignant glioma
Glioblastoma Multiforme
natural Tregs
Tumor induced Tregs.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00116/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00116/full

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