Blood Outgrowth and Proliferation of Endothelial Colony Forming Cells are Related to Markers of Disease Severity in Patients with Pulmonary Arterial Hypertension

Blood Outgrowth and Proliferation of Endothelial Colony Forming Cells are Related to Markers of Disease Severity in Patients with Pulmonary Arterial Hypertension

In pulmonary arterial hypertension (PAH), lung-angioproliferation leads to increased pulmonary vascular resistance, while simultaneous myocardial microvessel loss contributes to right ventricular (RV) failure. Endothelial colony forming cells (ECFC) are highly proliferative, angiogenic cells that ma...

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Bibliographic Details
Main Authors: Josien Smits, Dimitar Tasev, Stine Andersen, Robert Szulcek, Liza Botros, Steffen Ringgaard, Asger Andersen, Anton Vonk-Noordegraaf, Pieter Koolwijk, Harm Jan Bogaard
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
pulmonary hypertension
pulmonary vascular disease
endothelial colony forming cell
endothelial progenitor cell
Online Access:https://www.mdpi.com/1422-0067/19/12/3763

Internet

https://www.mdpi.com/1422-0067/19/12/3763

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