Synthetic surface for expansion of human mesenchymal stem cells in xeno-free, chemically defined culture conditions.

Human mesenchymal stem cells (HMSCS) possess three properties of great interest for the development of cell therapies and tissue engineering: multilineage differentiation, immunomodulation, and production of trophic factors. Efficient ex vivo expansion of hMSCs is a challenging requirement for large...

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Bibliographic Details
Main Authors: Paula J Dolley-Sonneville, Lori E Romeo, Zara K Melkoumian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734034?pdf=render