Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Abstract The outbreak of SARS-CoV-2 (2019-nCoV) virus has highlighted the need for fast and efficacious vaccine development. Stimulation of a proper immune response that leads to protection is highly dependent on presentation of epitopes to circulating T-cells via the HLA complex. SARS-CoV-2 is a la...

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Bibliographic Details
Main Authors: Marek Prachar, Sune Justesen, Daniel Bisgaard Steen-Jensen, Stephan Thorgrimsen, Erik Jurgons, Ole Winther, Frederik Otzen Bagger
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77466-4

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https://doi.org/10.1038/s41598-020-77466-4

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