Suppression of store-operated calcium entry causes dilated cardiomyopathy of the Drosophila heart

Suppression of store-operated calcium entry causes dilated cardiomyopathy of the Drosophila heart

Store-operated Ca2+ entry (SOCE) is an essential Ca2+ signaling mechanism present in most animal cells. SOCE refers to Ca2+ influx that is activated by depletion of sarco/endoplasmic reticulum (S/ER) Ca2+ stores. The main components of SOCE are STIM and Orai. STIM proteins function as S/ER Ca2+ sens...

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Bibliographic Details
Main Authors: Courtney E. Petersen, Matthew J. Wolf, Jeremy T. Smyth
Format: Article
Language:English
Published: The Company of Biologists 2020-03-01
Series:Biology Open
Subjects:
cardiomyopathy
cardiac
store-operated calcium entry
stim
orai
drosophila
Online Access:http://bio.biologists.org/content/9/3/bio049999

Internet

http://bio.biologists.org/content/9/3/bio049999

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