Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064

Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064

Clavulanic acid (CA) is a powerful inhibitor of the beta-lactamases, enzymes produced by bacteria resistants to penicillin and cefalosporin. This molecule is produced industrially by strains of Streptomyces clavuligerus in complex media which carbon and nitrogen resources are supplied by inexpensive...

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Bibliographic Details
Main Authors: Eliton da Silva Vasconcelos, Vanderlei Aparecido de Lima, Leandro Seiji Goto, Isara Lourdes Cruz-Hernández, Carlos Osamu Hokka
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2013-12-01
Series:Brazilian Journal of Microbiology
Subjects:
clavulanic acid
Streptomyces clavuligerus
mutation
lipase
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400005&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400005&lng=en&tlng=en

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