DNA Methyltransferases Modulate Hepatogenic Lineage Plasticity of Mesenchymal Stromal Cells

DNA Methyltransferases Modulate Hepatogenic Lineage Plasticity of Mesenchymal Stromal Cells

The irreversibility of developmental processes in mammalian cells has been challenged by rising evidence that de-differentiation of hepatocytes occurs in adult liver. However, whether reversibility exists in mesenchymal stromal cell (MSC)-derived hepatocytes (dHeps) remains elusive. In this study, w...

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Bibliographic Details
Main Authors: Chien-Wei Lee, Wei-Chih Huang, Hsien-Da Huang, Yi-Hsiang Huang, Jennifer H. Ho, Muh-Hwa Yang, Vincent W. Yang, Oscar K. Lee
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Stem Cell Reports
Subjects:
DNA methyltransferases
hepatocyte
de-differentiation
lineage conversion
plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117302151

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http://www.sciencedirect.com/science/article/pii/S2213671117302151

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