Transcriptome Analysis Reveals the AhR, Smad2/3, and HIF-1α Pathways as the Mechanism of Ochratoxin A Toxicity in Kidney Cells

Ochratoxin A (OTA) is a mycotoxin occurring in foods consumed by humans. Recently, there has been growing global concern regarding OTA toxicity. The main target organ of OTA is the kidney, but the mechanism underlying renal toxicity is not well known. In this study, human-derived proximal tubular ep...

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Bibliographic Details
Main Authors: Min Cheol Pyo, In-Geol Choi, Kwang-Won Lee
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/3/190