Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway

Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway

Meteorin-like (METRNL) protein is a newly identified myokine that functions to modulate energy expenditure and inflammation in adipose tissue. Herein, we aim to investigate the potential role and molecular basis of METRNL in doxorubicin (DOX)-induced cardiotoxicity. METRNL was found to be abundantly...

Full description

Bibliographic Details
Main Authors: Can Hu, Xin Zhang, Peng Song, Yu-Pei Yuan, Chun-Yan Kong, Hai-Ming Wu, Si-Chi Xu, Zhen-Guo Ma, Qi-Zhu Tang
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Doxorubicin
METRNL
Oxidative stress
Apoptosis
SIRT1
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309526

Internet

http://www.sciencedirect.com/science/article/pii/S2213231720309526

Similar Items