Isocitrate dehydrogenase 1 and 2 genes mutations and MGMT methylation in gliomas

Isocitrate dehydrogenase 1 and 2 genes mutations and MGMT methylation in gliomas

Gliomas are the most common brain tumors. It is difficult to detect them at early stages of disease and there is a few available therapies providing significant improvement in survival. Mutations of isocitrate dehydrogenase 1 and 2 genes (IDH1 and IDH2) play significant role in gliomogenesis, diagno...

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Bibliographic Details
Main Authors: D. V. Tabakov, A. N. Katargin, A. M. Stroganova, A. I. Senderovich, D. R. Naskhletashvili, N. P. Kiseljova
Format: Article
Language:Russian
Published: ABV-press 2017-04-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
glioma
idh1 and idh2 mutations
mgmt methylation
dna melting
Online Access:https://umo.abvpress.ru/jour/article/view/89

Internet

https://umo.abvpress.ru/jour/article/view/89

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