Endothelin-1 Enhances Superoxide and Prostaglandin E2 Production of Isolated Diabetic Glomeruli

Endothelin-1 (ET-1) plays an important role in the pathogenic mechanism of diabetic nephropathy. However, the regulatory effects of ET-1 on superoxide and prostaglandin E2 (PGE2) in diabetic glomeruli are unclear. The aim of this study was to determine whether ET-1 exerts a differential effect on th...

Full description

Bibliographic Details
Main Authors: Jia-Jung Lee, Chi-Chih Hung, Jer-Chia Tsai, Hung-Chun Chen
Format: Article
Language:English
Published: Wiley 2010-07-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X10700589