New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells

The groundbreaking CRISPR technology is revolutionizing biomedical research with its superior simplicity, high efficiency, and robust accuracy. Recent technological advances by a coupling CRISPR system with various DNA repair mechanisms have further opened up new opportunities to overcome existing c...

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Bibliographic Details
Main Authors: Xiangjun He, Yin-Xiong Li, Bo Feng
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/9465028