Claudin-5 Affects Endothelial Autophagy in Response to Early Hypoxia

Hypoxic injury to cerebrovascular endothelial cells (ECs) after stroke leads to blood-brain barrier (BBB) dysfunction, which is commonly associated with disruptions of endothelial tight junctions (TJs) and increased permeability. Therefore, maintaining the structural integrity and proper function of...

Full description

Bibliographic Details
Main Authors: Ping Yu, Yanyu Li, Gaoliang Zhong, Wen Li, Bing Chen, Jingjing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.737474/full