Development of a Single-Step Subtraction Method for Eukaryotic 18S and 28S Ribonucleic Acids

The abundance of mammalian 18S and 28S ribosomal RNA can decrease the detection sensitivity of bacterial or viral targets in complex host-pathogen mixtures. A method to capture human RNA in a single step was developed and characterized to address this issue. For this purpose, capture probes were cov...

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Bibliographic Details
Main Authors: Marie J. Archer, Baochuan Lin
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2011/910369