Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV-infected patients.

Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been reported to improve the accuracy of TB diagnosis.We enrolled HIV-infected adults with coug...

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Bibliographic Details
Main Authors: Adithya Cattamanchi, Isaac Ssewenyana, Rose Nabatanzi, Cecily R Miller, Saskia Den Boon, J Lucian Davis, Alfred Andama, William Worodria, Samuel D Yoo, Huyen Cao, Laurence Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3383728?pdf=render