Induction of cancer stem cell properties in colon cancer cells by defined factors.

Cancer stem cells (CSCs) are considered to be responsible for the dismal prognosis of cancer patients. However, little is known about the molecular mechanisms underlying the acquisition and maintenance of CSC properties in cancer cells because of their rarity in clinical samples. We herein induced C...

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Bibliographic Details
Main Authors: Nobu Oshima, Yasuhiro Yamada, Satoshi Nagayama, Kenji Kawada, Suguru Hasegawa, Hiroshi Okabe, Yoshiharu Sakai, Takashi Aoi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090165?pdf=render