A comparison of cost effectiveness using data from randomized trials or actual clinical practice: selective cox-2 inhibitors as an example.

Data on absolute risks of outcomes and patterns of drug use in cost-effectiveness analyses are often based on randomised clinical trials (RCTs). The objective of this study was to evaluate the external validity of published cost-effectiveness studies by comparing the data used in these studies (typi...

Full description

Bibliographic Details
Main Authors: Tjeerd-Pieter van Staa, Hubert G Leufkens, Bill Zhang, Liam Smeeth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2779340?pdf=render