Expression of multiple transgenes from a single construct using viral 2A peptides in Drosophila.

Expression of multiple reporter or effector transgenes in the same cell from a single construct is increasingly necessary in various experimental paradigms. The discovery of short, virus-derived peptide sequences that mediate a ribosome-skipping event enables generation of multiple separate peptide...

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Bibliographic Details
Main Authors: Richard W Daniels, Adam J Rossano, Gregory T Macleod, Barry Ganetzky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4063965?pdf=render