New emerging targets in cancer immunotherapy: the role of LAG3

The success of immunotherapy in many disease entities is limited to a specific subpopulation of patients. To overcome this problem, dual blockade treatments mainly against cytotoxic T-lymphocyte-associated protein 4 (CTLA4) and programmed cell death receptor (ligand) 1 (PD-(L)1) axis were developed....

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Bibliographic Details
Main Authors: Hannah Christina Puhr, Aysegül Ilhan-Mutlu
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/4/2/e000482.full