Newborn blood DNA epigenetic variations and signaling pathway genes associated with Tetralogy of Fallot (TOF).

Tetralogy of Fallot (TOF) is the most common Critical Congenital Heart Defect (CCHD). The etiology of TOF is unknown in most cases. Preliminary data from our group and others suggest that epigenetic changes may play an important role in CHD. Epidemiologically, a significant percentage of CHD includi...

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Main Authors: Uppala Radhakrishna, Sangeetha Vishweswaraiah, Avinash M Veerappa, Rita Zafra, Samet Albayrak, Prajna H Sitharam, Nazia M Saiyed, Nitish K Mishra, Chittibabu Guda, Ray Bahado-Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6136787?pdf=render