From DNA Sequences to Chemical Structures – Methods for Mining Microbial Genomic and Metagenomic Data Sets for New Natural Products

From DNA Sequences to Chemical Structures – Methods for Mining Microbial Genomic and Metagenomic Data Sets for New Natural Products

Rapid mining of large genomic and metagenomic data sets for modular polyketide synthases, non-ribosomal peptide synthetases and hybrid polyketide synthase/non-ribosomal peptide synthetase biosynthetic gene clusters has been achieved using the generic computer program packages ClustScan and CompGen....

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Bibliographic Details
Main Authors: Jurica Zucko, Antonio Starcevic, Janko Diminic, Mouhsine Elbekali, Mohamed Lisfi, Paul F. Long, John Cullum, Daslav Hranueli
Format: Article
Language:English
Published: University of Zagreb 2010-01-01
Series:Food Technology and Biotechnology
Subjects:
polyketides
non-ribosomal peptides
Actinobacteria
homologous recombination
Online Access:http://hrcak.srce.hr/file/81787

Internet

http://hrcak.srce.hr/file/81787

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