Synthesis, Structural and Pharmacological Characterizations of CIC, a Novel α-Conotoxin with an Extended N-terminal Tail

Cone snails are venomous marine predators that rely on fast-acting venom to subdue their prey and defend against aggressors. The conotoxins produced in the venom gland are small disulfide-rich peptides with high affinity and selectivity for their pharmacological targets. A dominant group comprises α...

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Bibliographic Details
Main Authors: Julien Giribaldi, Yves Haufe, Edward R. J. Evans, David T. Wilson, Norelle L. Daly, Christine Enjalbal, Annette Nicke, Sébastien Dutertre
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/19/3/141