sEst: Accurate Sex-Estimation and Abnormality Detection in Methylation Microarray Data

DNA methylation influences predisposition, development and prognosis for many diseases, including cancer. However, it is not uncommon to encounter samples with incorrect sex labelling or atypical sex chromosome arrangement. Sex is one of the strongest influencers of the genomic distribution of DNA m...

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Bibliographic Details
Main Authors: Chol-Hee Jung, Daniel J. Park, Peter Georgeson, Khalid Mahmood, Roger L. Milne, Melissa C. Southey, Bernard J. Pope
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/10/3172