Chemotherapy-triggered changes in stromal compartment drive tumor invasiveness and progression of breast cancer

Chemotherapy-triggered changes in stromal compartment drive tumor invasiveness and progression of breast cancer

Abstract Background Chemotherapy remains a standard treatment option for breast cancer despite its toxic effects to normal tissues. However, the long-lasting effects of chemotherapy on non-malignant cells may influence tumor cell behavior and response to treatment. Here, we have analyzed the effects...

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Bibliographic Details
Main Authors: Jana Plava, Monika Burikova, Marina Cihova, Lenka Trnkova, Bozena Smolkova, Pavel Babal, Lucia Krivosikova, Pavol Janega, Lucia Rojikova, Slavka Drahosova, Martin Bohac, Lubos Danisovic, Lucia Kucerova, Svetlana Miklikova
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Breast cancer
Mesenchymal stromal cells
Chemotherapy
Tumor microenvironment
Cancer progression
Online Access:https://doi.org/10.1186/s13046-021-02087-2

Internet

https://doi.org/10.1186/s13046-021-02087-2

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