Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones

<p>Abstract</p> <p>The neuropeptide substance-P (SP) is expressed from the TAC1 gene in sensory neurones where it acts as a key modulator of neurogenic inflammation. The promoter of TAC1 (TAC1prom) plays a central role in the regulation of the TAC1 gene but requires the presence of...

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Bibliographic Details
Main Authors: Ross Ruth, Davidson Scott, Lear Marissa, Shanley Lynne, MacKenzie Alasdair
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/10