“Upstream Analysis”: An Integrated Promoter-Pathway Analysis Approach to Causal Interpretation of Microarray Data

A strategy is presented that allows a causal analysis of co-expressed genes, which may be subject to common regulatory influences. A state-of-the-art promoter analysis for potential transcription factor (TF) binding sites in combination with a knowledge-based analysis of the upstream pathway that co...

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Bibliographic Details
Main Authors: Jeannette Koschmann, Anirban Bhar, Philip Stegmaier, Alexander E. Kel, Edgar Wingender
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Microarrays
Subjects:
Online Access:http://www.mdpi.com/2076-3905/4/2/270