IDO2: A Pathogenic Mediator of Inflammatory Autoimmunity

Indoleamine 2,3-dioxygenase 2 (IDO2), a homolog of the better-studied tryptophan-catabolizing enzyme IDO1, is an immunomodulatory molecule with potential effects on various diseases including cancer and autoimmunity. Here, we review what is known about the direct connections between IDO2 and immune...

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Bibliographic Details
Main Authors: Lauren M.F. Merlo, Laura Mandik-Nayak
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Clinical Medicine Insights: Pathology
Online Access:https://doi.org/10.4137/CPath.S39930