PAF enhances MMP-2 production in rat aortic VSMCs via a β-arrestin2-dependent ERK signaling pathway[S]

PAF enhances MMP-2 production in rat aortic VSMCs via a β-arrestin2-dependent ERK signaling pathway[S]

Platelet-activating factor (PAF), 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine, is a potent phospholipid mediator and has been reported to be localized in atherosclerotic plaque. However, its role in the progression of atherosclerosis remains unclear. In the present study, we investigated the role...

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Bibliographic Details
Main Authors: Yun H. Kim, Seung J. Lee, Kyo W. Seo, Jin U. Bae, So Y. Park, Eun K. Kim, Sun S. Bae, Jae H. Kim, Chi D. Kim
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Journal of Lipid Research
Subjects:
platelet-activating factor
platelet-activating factor receptor
β-arrestin2
extracellular signal-regulated kinase
matrix metalloproteinase-2
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352949

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http://www.sciencedirect.com/science/article/pii/S0022227520352949

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